Our DNA Can Hint at Heart Risks Early. We Decode Those Signals
We analyse both inherited genes and your overall polygenic risk to understand your heart’s long-term tendencies. With NGS and PRS, you get clear, personalised insights so you can take the right preventive steps
Why It’s Important?
The Stats You Can’t Ignore
CENT AI is built on clinical evidence and not assumptions. These genetic facts explain why early, accurate DNA analysis truly matters.
40–60% of the risk of coronary artery disease (CAD) is estimated to be heritable based on twin and family studies
Source: AHA
What all gets covered?
Comprehensive Genetic Screening for Heart Disease
Most genetic screening stop at the surface where as CENT AI goes deeper by combining both NGS and PRS. We detect what others often miss
Coronary Artery Disease
Inherited tendency to develop heart blockages or heart attacks.
PRS
What We Test For
PRS measures your genome-wide inherited risk of coronary artery disease, helping estimate your lifetime likelihood of heart blockages
Key Genes Analyzed
Genome-wide SNP markers associated with CAD
Arrhythmogenic Cardiomyopathy
Inherited Scarring of the heart muscle.
NGS
What We Test For
NGS identifies high-impact mutations linked to arrhythmogenic cardiomyopathy, which can increase the risk of ventricular arrhythmias and sudden cardiac events
Key Genes Analyzed
PKP2
DSP
DSG2
DSC2
JUP
LMNA
FLNC
PLN
Long QT Syndrome
A genetic electrical disorder that causes the heart to take longer to reset between beats
NGS
What We Test For
NGS detects pathogenic variants in cardiac ion-channel genes that cause Long QT Syndrome, increasing the risk of fainting and dangerous arrhythmias.
Key Genes Analyzed
KCNQ1
KCNH2
SCN5A
KCNE1
KCNE2
Hypertrophic Cardiomyopathy
Inherited thickening of the heart muscle
NGS
What We Test For
NGS screens for mutations in sarcomere genes that cause hypertrophic cardiomyopathy, helping detect hereditary forms early.
Key Genes Analyzed
MYH7
MYBPC3
TNNT2
TNNI3
TPM1
CTC1
Dilated Cardiomyopathy
A genetic condition where the heart becomes enlarged and weak
NGS
What We Test For
NGS evaluates genes associated with dilated cardiomyopathy, identifying inherited variants that weaken heart muscle function.
Key Genes Analyzed
TTN
LMNA
BAG3
PLN
RBM20
DES
TNNT2
Hypercholesterolemia
Your inherited tendency to have high LDL
PRS
What We Test For
PRS measures your broader genetic tendency for high LDL cholesterol.
Key Genes Analyzed
genome-wide SNP markers for LDL
FAQ
Frequently Asked Questions
This screening analyses your DNA across all four major disease systems—Heart, Cancer, Neuro, and Metabolic—using both Next-Generation Sequencing (NGS) for high-impact genes and Polygenic Risk Scoring (PRS) for common, multi-gene risks.
Since your DNA doesn’t change, genetics is typically a once-in-a-lifetime test.
But your personalised screening plan is updated as medical science evolves.
Yes. Genetics allows you to:
Detect risks decades before symptoms
Personalise screening (MRI frequency, calcium score, cancer surveillance, etc.)
Modify lifestyle based on your actual biology
Take early actions that can reduce risk by 30–70%, depending on the condition
Most consumer DNA tests only analyse a few markers or ancestry data.
CENT AI performs clinical-grade sequencing + PRS across thousands of markers and medically important genes—validated for preventive healthcare, not recreation.
